Director, Local Study Operations Manager

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

What you will do

Let’s do this. Let’s change the world. In this vital role you will provide strategic and operational leadership for the country LSOM organization and is accountable for the quality, timeliness, cost, and compliant execution of the country clinical study portfolio. The role achieves results through LSOM Senior Managers and their FTE and FSP teams, translating global clinical development strategy into country operating priorities. The role directs portfolio delivery, resource and capacity strategy, financial planning, quality and risk management, vendor performance, and inspection readiness from feasibility through study close-out. As a member of the country leadership team, this role influences study placement and portfolio decisions, leads the resolution of significant operational issues, develops organizational capability and succession plans, and represents LSOM operations in country, regional, and global governance forums.

Accountabilities

Lead the successful delivery of the country study portfolio through the LSOM management organization, ensuring alignment with global clinical development priorities.

Provides strategic direction and leadership to LSOM country organization across the full study lifecycle, including feasibility, study execution, and study close-out.

Establishes portfolio-level oversight of delivery, quality, risk, timelines, and performance, directing timely escalation and resolution of critical issues for LSOM management organization.

Manage LSOM and LSOM vendor performance to guarantee high-quality study execution, serving as the primary escalation point for local study challenges, driving solutions, and ensuring portfolio targets are met within the country.

Build leadership capability within the LSOM organization through targeted coaching, development, and succession planning, preparing LSOMs to lead increasingly complex trials and programs.

Establishes strong operating partnerships with Clinical Research Associate (CRA) organization to support study start-up, monitoring, issue resolution, and compliant trial execution across the country portfolio.

Cultivate a high-performing, accountable, and inclusive organization focused on operational excellence and continuous improvement.

Champion strong integration between study strategy and local execution teams to translate portfolio priorities into effective country-level delivery.

Strengthen cross-functional alignment and accountability across country teams to accelerate execution and deliver portfolio commitments.